Glycine-Amide Is an Active Metabolite of the Antiretroviral Tripeptide Glycyl-Prolyl-Glycine-Amide

The chemically modified tripeptide glycyl-prolyl-glycine-amide (GPG-NH(2)) inhibits replication of human immunodeficiency virus (HIV) type 1 (HIV-1) in vitro, probably by interfering with capsid formation. The aim of the present study was to determine whether the metabolites glycyl-proline (GP-OH),...

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Bibliographic Details
Main Authors: Andersson, Elin, Horal, Peter, Jejcic, Alenka, Höglund, Stefan, Balzarini, Jan, Vahlne, Anders, Svennerholm, Bo
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC538866/
https://ncbi.nlm.nih.gov/pubmed/15616273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.40-44.2005
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