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Stress-induced polyubiquitination of proteasomal ubiquitin receptors targets the proteolytic complex for autophagic degradation

Ubiquitin (Ub) is a small protein (8 kDa) found in all eukaryotic cells, which is conjugated covalently to numerous proteins, tagging them for recognition by a downstream effector. One of the best characterized functions of Ub is targeting proteins for either selective degradation by the proteasome,...

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Pubblicato in:Autophagy
Autori principali: Cohen-Kaplan, Victoria, Ciechanover, Aaron, Livneh, Ido
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388213/
https://ncbi.nlm.nih.gov/pubmed/28121483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1278327
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