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Stress-induced polyubiquitination of proteasomal ubiquitin receptors targets the proteolytic complex for autophagic degradation

Ubiquitin (Ub) is a small protein (8 kDa) found in all eukaryotic cells, which is conjugated covalently to numerous proteins, tagging them for recognition by a downstream effector. One of the best characterized functions of Ub is targeting proteins for either selective degradation by the proteasome,...

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Библиографические подробности
Опубликовано в: :Autophagy
Главные авторы: Cohen-Kaplan, Victoria, Ciechanover, Aaron, Livneh, Ido
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388213/
https://ncbi.nlm.nih.gov/pubmed/28121483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1278327
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