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Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription
Complex II inhibitors 3-nitropropionic acid (3NP) and malonate cause striatal damage reminiscent of Huntington's disease and have been shown to involve oxidative stress in their pathogenesis. Because nuclear factor erythroid 2-related factor 2 (Nrf2)-dependent transcriptional activation by mean...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC538748/ https://ncbi.nlm.nih.gov/pubmed/15611470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408487101 |
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