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Astrocyte-Specific Overexpression of Nrf2 Protects Striatal Neurons from Mitochondrial Complex II Inhibition

Nuclear factor E2-related factor 2 (Nrf2) is a transcription factor that is known to regulate a variety of cytoprotective genes through the antioxidant response element (ARE). This endogenous response is one of the major pathways by which cells are protected from xenobiotic or innate oxidative insul...

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Detalhes bibliográficos
Main Authors: Calkins, Marcus J., Vargas, Marcelo R., Johnson, Delinda A., Johnson, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871759/
https://ncbi.nlm.nih.gov/pubmed/20211941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq072
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