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Targeted disruption of Nrf2 causes regenerative immune-mediated hemolytic anemia

A basic leucine zipper transcription factor, NF-E2-related factor 2 (Nrf2), plays a critical role in the cellular defense mechanism by mediating a coordinate up-regulation of antioxidant responsive element-driven detoxification and antioxidant genes. Here, we report that targeted disruption of Nrf2...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Jong-Min, Chan, Kaimin, Kan, Yuet Wai, Johnson, Jeffrey A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC470746/
https://ncbi.nlm.nih.gov/pubmed/15210949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403620101
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