Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway

Aging is a major international concern that brings formidable socioeconomic and healthcare challenges. Small molecules capable of improving the health of older individuals are being explored. Small molecules that enhance cellular stress resistance are a promising avenue to alleviate declines seen in...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Fang, Evandro F., Waltz, Tyler B., Kassahun, Henok, Lu, Qiping, Kerr, Jesse S., Morevati, Marya, Fivenson, Elayne M., Wollman, Bradley N., Marosi, Krisztina, Wilson, Mark A., Iser, Wendy B., Eckley, D. Mark, Zhang, Yongqing, Lehrmann, Elin, Goldberg, Ilya G., Scheibye-Knudsen, Morten, Mattson, Mark P., Nilsen, Hilde, Bohr, Vilhelm A., Becker, Kevin G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387417/
https://ncbi.nlm.nih.gov/pubmed/28397803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46208
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