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DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning

Recent technological advances have enabled DNA methylation to be assayed at single-cell resolution. However, current protocols are limited by incomplete CpG coverage and hence methods to predict missing methylation states are critical to enable genome-wide analyses. We report DeepCpG, a computationa...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Angermueller, Christof, Lee, Heather J., Reik, Wolf, Stegle, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387360/
https://ncbi.nlm.nih.gov/pubmed/28395661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1189-z
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