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Viral Transport of DNA Damage That Mimics a Stalled Replication Fork
Adeno-associated virus type 2 (AAV2) infection incites cells to arrest with 4N DNA content or die if the p53 pathway is defective. This arrest depends on AAV2 DNA, which is single stranded with inverted terminal repeats that serve as primers during viral DNA replication. Here, we show that AAV2 DNA...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC538728/ https://ncbi.nlm.nih.gov/pubmed/15596849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.1.569-580.2005 |
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