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Tiamulin inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of CD73

BACKGROUND: Metastasis is the leading cause of death in breast cancer patients. CD73, also known as ecto-5′-nucleotidase, plays a critical role in cancer development including metastasis. The existing researches indicate that overexpression of CD73 promotes growth and metastasis of breast cancer. Th...

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Pubblicato in:BMC Cancer
Autori principali: Yang, Xu, Pei, Shimin, Wang, Huanan, Jin, Yipeng, Yu, Fang, Zhou, Bin, Zhang, Hong, Zhang, Di, Lin, Degui
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387263/
https://ncbi.nlm.nih.gov/pubmed/28399915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3250-4
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