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CD8(+) T-Cell-Mediated Cross-Clade Protection in the Genital Tract following Intranasal Immunization with Inactivated Human Immunodeficiency Virus Antigen Plus CpG Oligodeoxynucleotides
Human immunodeficiency virus (HIV) is a mucosally transmitted infection that rapidly targets and depletes CD4(+) T cells in mucosal tissues and establishes a major reservoir for viral persistence in gut-associated lymphoid tissues. Therefore, vaccines designed to prevent HIV infections must induce p...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC538685/ https://ncbi.nlm.nih.gov/pubmed/15596832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.1.393-400.2005 |
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