CD8(+) T-Cell-Mediated Cross-Clade Protection in the Genital Tract following Intranasal Immunization with Inactivated Human Immunodeficiency Virus Antigen Plus CpG Oligodeoxynucleotides

Human immunodeficiency virus (HIV) is a mucosally transmitted infection that rapidly targets and depletes CD4(+) T cells in mucosal tissues and establishes a major reservoir for viral persistence in gut-associated lymphoid tissues. Therefore, vaccines designed to prevent HIV infections must induce p...

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Detalhes bibliográficos
Main Authors: Jiang, Janina Q., Patrick, Amy, Moss, Ronald B., Rosenthal, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538685/
https://ncbi.nlm.nih.gov/pubmed/15596832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.1.393-400.2005
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