EAF2 regulates DNA repair through Ku70/Ku80 in the prostate

Androgens are known to protect prostate cancer cells from DNA damage. Recent studies showed regulation of DNA repair genes by androgen receptor signaling in prostate cancers. ELL-associated factor 2 (EAF2) is an androgen-regulated tumor suppressor and its intracellular localization can be modulated...

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Gepubliceerd in:Oncogene
Hoofdauteurs: Ai, J, Pascal, L E, Wei, L, Zang, Y, Zhou, Y, Yu, X, Gong, Y, Nakajima, S, Nelson, J B, Levine, A S, Lan, L, Wang, Z
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386836/
https://ncbi.nlm.nih.gov/pubmed/27721405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.373
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