Ketamine up-regulates a cluster of intronic miRNAs within the serotonin receptor 2C gene by inhibiting glycogen synthase kinase-3

OBJECTIVES: We examined mechanisms that contribute to the rapid antidepressant effect of ketamine in mice that is dependent on glycogen synthase kinase-3 (GSK3) inhibition. METHODS: We measured serotonergic (5HT)-2C-receptor (5HTR2C) cluster microRNA (miRNA) levels in mouse hippocampus after adminis...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:World J Biol Psychiatry
Main Authors: Grieco, Steven F., Velmeshev, Dmitry, Magistri, Marco, Eldar-Finkelman, Hagit, Faghihi, Mohammad A., Jope, Richard S., Beurel, Eleonore
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386835/
https://ncbi.nlm.nih.gov/pubmed/27723376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15622975.2016.1224927
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados