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Up-regulation of insulin-like growth factor 2 by ketamine requires glycogen synthase kinase-3 inhibition
An antidepressant dose of the rapidly-acting ketamine inhibits glycogen synthase kinase-3 (GSK3) in mouse hippocampus, and this inhibition is required for the antidepressant effect of ketamine in learned helplessness depression-like behavior. Here we report that treatment with an antidepressant dose...
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| Gepubliceerd in: | Prog Neuropsychopharmacol Biol Psychiatry |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5061618/ https://ncbi.nlm.nih.gov/pubmed/27542584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2016.08.008 |
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