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Tissue transglutaminase induces Epithelial-Mesenchymal-Transition and the acquisition of stem cell like characteristics in colorectal cancer cells

Human colon cancer cell lines (CRCs) RKO, SW480 and SW620 were investigated for TG2 involvement in tumour advancement and aggression. TG2 expression correlated with tumour advancement and expression of markers of epithelial-mesenchymal transition (EMT). The metastatic cell line SW620 showed high TG2...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Ayinde, Oluseyi, Wang, Zhuo, Griffin, Martin
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386741/
https://ncbi.nlm.nih.gov/pubmed/28223538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15370
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