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Tissue transglutaminase induces Epithelial-Mesenchymal-Transition and the acquisition of stem cell like characteristics in colorectal cancer cells

Human colon cancer cell lines (CRCs) RKO, SW480 and SW620 were investigated for TG2 involvement in tumour advancement and aggression. TG2 expression correlated with tumour advancement and expression of markers of epithelial-mesenchymal transition (EMT). The metastatic cell line SW620 showed high TG2...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ayinde, Oluseyi, Wang, Zhuo, Griffin, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386741/
https://ncbi.nlm.nih.gov/pubmed/28223538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15370
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