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Rv2299c, a novel dendritic cell-activating antigen of Mycobacterium tuberculosis, fused-ESAT-6 subunit vaccine confers improved and durable protection against the hypervirulent strain HN878 in mice

Understanding functional interactions between DCs and antigens is necessary for achieving an optimal and desired immune response during vaccine development. Here, we identified and characterized protein Rv2299c (heat-shock protein 90 family), which effectively induced DC maturation. The Rv2299c-matu...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Choi, Han-Gyu, Choi, Seunga, Back, Yong Woo, Paik, Seungwha, Park, Hye-Soo, Kim, Woo Sik, Kim, Hongmin, Cha, Seung Bin, Choi, Chul Hee, Shin, Sung Jae, Kim, Hwa-Jung
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386736/
https://ncbi.nlm.nih.gov/pubmed/28193909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15256
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