Rv2299c, a novel dendritic cell-activating antigen of Mycobacterium tuberculosis, fused-ESAT-6 subunit vaccine confers improved and durable protection against the hypervirulent strain HN878 in mice

Understanding functional interactions between DCs and antigens is necessary for achieving an optimal and desired immune response during vaccine development. Here, we identified and characterized protein Rv2299c (heat-shock protein 90 family), which effectively induced DC maturation. The Rv2299c-matu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Choi, Han-Gyu, Choi, Seunga, Back, Yong Woo, Paik, Seungwha, Park, Hye-Soo, Kim, Woo Sik, Kim, Hongmin, Cha, Seung Bin, Choi, Chul Hee, Shin, Sung Jae, Kim, Hwa-Jung
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386736/
https://ncbi.nlm.nih.gov/pubmed/28193909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15256
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