Mitotic control of human papillomavirus genome-containing cells is regulated by the function of the PDZ-binding motif of the E6 oncoprotein

The function of a conserved PDS95/DLG1/ZO1 (PDZ) binding motif (E6 PBM) at the C-termini of E6 oncoproteins of high-risk human papillomavirus (HPV) types contributes to the development of HPV-associated malignancies. Here, using a primary human keratinocyte-based model of the high-risk HPV18 life cy...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Marsh, Elizabeth K., Delury, Craig P., Davies, Nicholas J., Weston, Christopher J., Miah, Mohammed A.L., Banks, Lawrence, Parish, Joanna L., Higgs, Martin R, Roberts, Sally
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386700/
https://ncbi.nlm.nih.gov/pubmed/28061478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14469
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