The Role of Protein Kinase A Regulation of the E6 PDZ-Binding Domain during the Differentiation-Dependent Life Cycle of Human Papillomavirus Type 18

Human papillomavirus (HPV) E6 proteins of high-risk alpha types target a select group of PSD95/DLG1/ZO1 (PDZ) domain-containing proteins by using a C-terminal PDZ-binding motif (PBM), an interaction that can be negatively regulated by phosphorylation of the E6 PBM by protein kinase A (PKA). Here, we...

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Detalhes bibliográficos
Main Authors: Delury, Craig P., Marsh, Elizabeth K., James, Claire D., Boon, Siaw Shi, Banks, Lawrence, Knight, Gillian L., Roberts, Sally
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754118/
https://ncbi.nlm.nih.gov/pubmed/23804647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01234-13
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