Selenite inhibits glutamine metabolism and induces apoptosis by regulating GLS1 protein degradation via APC/C-CDH1 pathway in colorectal cancer cells

Glutaminolysis is important for metabolism and biosynthesis of cancer cells, and GLS is essential in the process. Selenite is widely regarded as a chemopreventive agent against cancer risk. Emerging evidence suggests that it also has chemotherapeutic potential in various cancer types, but the mechan...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhao, Junzhang, Zhou, Rui, Hui, Kaiyuan, Yang, Yang, Zhang, QiuYue, Ci, Yali, Shi, Lei, Xu, Caimin, Huang, Fang, Hu, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386651/
https://ncbi.nlm.nih.gov/pubmed/27902968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13600
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados