Hydrogen sulfide promotes autophagy of hepatocellular carcinoma cells through the PI3K/Akt/mTOR signaling pathway

Hydrogen sulfide (H(2)S), in its gaseous form, plays an important role in tumor carcinogenesis. This study investigated the effects of H(2)S on the cell biological functions of hepatocellular carcinoma (HCC). HCC cell lines, HepG2 and HLE, were treated with NaHS, a donor of H(2)S, and rapamycin, a c...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Shanshan S, Chen, Yuhan H, Chen, Ning, Wang, Lijun J, Chen, Dexi X, Weng, Honglei L, Dooley, Steven, Ding, Huiguo G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386547/
https://ncbi.nlm.nih.gov/pubmed/28333142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.18
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