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Hydrogen sulfide ameliorates doxorubicin-induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway

The present study aimed to determine the role and regulatory mechanism of hydrogen sulfide (H(2)S) in the amelioration of doxorubicin-induced myocardial fibrosis in rats. It is hypothesized that the PI3K/AKT/mTOR signaling pathway is regulated to inhibit endoplasmic reticulum stress (ERS) and autoph...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Nie, Liangui, Liu, Maojun, Chen, Jian, Wu, Qian, Li, Yaling, Yi, Jiali, Zheng, Xia, Zhang, Jingjing, Chu, Chun, Yang, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930940/
https://ncbi.nlm.nih.gov/pubmed/33649809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.11938
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