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TNF-α-induced LRG1 promotes angiogenesis and mesenchymal stem cell migration in the subchondral bone during osteoarthritis

The incomplete understanding of aberrant neovascularization, which contributes to osteoarthritis suggests that additional modulators have yet to be identified. Our objective was to identify the role of Leucine-rich-alpha-2-glycoprotein1 (LRG1), a new regulator of pathogenic angiogenesis, in osteoart...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Yiyun, Xu, Jiajia, Zhang, Xudong, Wang, Chuandong, Huang, Yan, Dai, Kerong, Zhang, Xiaoling
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386532/
https://ncbi.nlm.nih.gov/pubmed/28358372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.129
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