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LRG1 modulates epithelial-mesenchymal transition and angiogenesis in colorectal cancer via HIF-1α activation

BACKGROUND: Leucine-rich-alpha-2-glycoprotein 1 (LRG1) has been reported to be involved in several tumors, whether it participates in colorectal cancer (CRC) progression remains unclear. Here, we investigated the biological function and underlying molecular mechanisms of LRG1 in CRC. METHODS: The mR...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Zhang, Jingjing, Zhu, Lingyin, Fang, Jingyuan, Ge, Zhizheng, Li, Xiaobo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746930/
https://ncbi.nlm.nih.gov/pubmed/26856989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0306-2
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