Targeted gene disruption of the endogenous c-abl locus by homologous recombination with DNA encoding a selectable fusion protein.

We have introduced a substitution mutation into the c-abl locus of murine embryonic stem cells by homologous recombination between exogenously added DNA and the endogenous gene. Model constructs were initially generated that consisted of a promoterless selectable neomycin resistance marker inserted...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Schwartzberg, P L, Robertson, E J, Goff, S P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53865/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2183226/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.8.3210
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!