BNIP3 upregulation via stimulation of ERK and JNK activity is required for the protection of keratinocytes from UVB-induced apoptosis

The human skin has an important role in barrier function. Ultraviolet rays (UV) from sunlight exposure can cause cell apoptosis in the skin epidermis, resulting in the disruption of the barrier. Previously, we have demonstrated that BNIP3 stimulates autophagy in epidermal keratinocytes and has a pro...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Moriyama, Mariko, Moriyama, Hiroyuki, Uda, Junki, Kubo, Hirokazu, Nakajima, Yuka, Goto, Arisa, Morita, Takashi, Hayakawa, Takao
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386491/
https://ncbi.nlm.nih.gov/pubmed/28151469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.4
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