BNIP3 upregulation via stimulation of ERK and JNK activity is required for the protection of keratinocytes from UVB-induced apoptosis

The human skin has an important role in barrier function. Ultraviolet rays (UV) from sunlight exposure can cause cell apoptosis in the skin epidermis, resulting in the disruption of the barrier. Previously, we have demonstrated that BNIP3 stimulates autophagy in epidermal keratinocytes and has a pro...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Moriyama, Mariko, Moriyama, Hiroyuki, Uda, Junki, Kubo, Hirokazu, Nakajima, Yuka, Goto, Arisa, Morita, Takashi, Hayakawa, Takao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386491/
https://ncbi.nlm.nih.gov/pubmed/28151469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.4
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