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Coupled excitable Ras and F-actin activation mediates spontaneous pseudopod formation and directed cell movement

Many eukaryotic cells regulate their mobility by external cues. Genetic studies have identified >100 components that participate in chemotaxis, which hinders the identification of the conceptual framework of how cells sense and respond to shallow chemical gradients. The activation of Ras occurs d...

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Publicat a:Mol Biol Cell
Autors principals: van Haastert, Peter J. M., Keizer-Gunnink, Ineke, Kortholt, Arjan
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385941/
https://ncbi.nlm.nih.gov/pubmed/28148648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-10-0733
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