Omega-3 Polyunsaturated Fatty Acids Attenuate Fibroblast Activation and Kidney Fibrosis Involving MTORC2 Signaling Suppression

Epidemiologic studies showed the correlation between the deficiency of omega-3 polyunsaturated fatty acids (n-3 PUFAs) and the progression of chronic kidney diseases (CKD), however, the role and mechanisms for n-3 PUFAs in protecting against kidney fibrosis remain obscure. In this study, NRK-49F cel...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Zeng, Zhifeng, Yang, Haiyuan, Wang, Ying, Ren, Jiafa, Dai, Yifan, Dai, Chunsun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385873/
https://ncbi.nlm.nih.gov/pubmed/28393852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46146
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