Chk1 inhibition potentiates the therapeutic efficacy of PARP inhibitor BMN673 in gastric cancer

Globally, gastric cancer is the second leading cause of cancer deaths because of the lack of effective treatments for patients with advanced tumors when curative surgery is not possible. Thus, there is an urgent need to identify molecular targets in gastric cancer that can be used for developing nov...

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Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Yin, Yuping, Shen, Qian, Zhang, Peng, Tao, Ruikang, Chang, Weilong, Li, Ruidong, Xie, Gengchen, Liu, Weizhen, Zhang, Lihong, Kapoor, Prabodh, Song, Shumei, Ajani, Jaffer, Mills, Gordon B, Chen, Jianying, Tao, Kaixiong, Peng, Guang
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385637/
https://ncbi.nlm.nih.gov/pubmed/28401005
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