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Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway

Accumulating evidence displays that an abnormal deposition of amyloid beta-peptide (Aβ) is the primary cause of the pathogenesis of Alzheimer's disease (AD). And therefore the elimination of Aβ is regarded as an important strategy for AD treatment. The discovery of drug candidates using culture...

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Bibliographic Details
Published in:Redox Biol
Main Authors: Zeng, Zhiwen, Xu, Jinying, Zheng, Wenhua
Format: Artigo
Language:Inglês
Published: Elsevier 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385605/
https://ncbi.nlm.nih.gov/pubmed/28391183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.04.003
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