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Metabolomic characterisation of the effects of oncogenic PIK3CA transformation in a breast epithelial cell line

Somatic mutations in PIK3CA are frequently found in a number of human cancers, including breast cancer, altering cellular physiology and tumour sensitivity to chemotherapy. This renders PIK3CA an attractive molecular target for early detection and personalised therapy. Using (1)H Nuclear Magnetic Re...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Lau, Chung-Ho E., Tredwell, Gregory D., Ellis, James K., Lam, Eric W.-F., Keun, Hector C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385542/
https://ncbi.nlm.nih.gov/pubmed/28393905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46079
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