Decreased Dependence on Receptor Recognition for the Fusion Promotion Activity of L289A-Mutated Newcastle Disease Virus Fusion Protein Correlates with a Monoclonal Antibody-Detected Conformational Change

It has been shown that the L289A-mutated Newcastle disease virus (NDV) fusion (F) protein gains the ability to promote fusion of Cos-7 cells independent of the viral hemagglutinin-neuraminidase (HN) protein and exhibits a 50% enhancement in HN-dependent fusion over wild-type (wt) F protein. Here, we...

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Bibliographic Details
Published in:J Virol
Main Authors: Li, Jianrong, Melanson, Vanessa R., Mirza, Anne M., Iorio, Ronald M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2005
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538552/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15613345/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.2.1180-1190.2005
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