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Decreased Dependence on Receptor Recognition for the Fusion Promotion Activity of L289A-Mutated Newcastle Disease Virus Fusion Protein Correlates with a Monoclonal Antibody-Detected Conformational Change

It has been shown that the L289A-mutated Newcastle disease virus (NDV) fusion (F) protein gains the ability to promote fusion of Cos-7 cells independent of the viral hemagglutinin-neuraminidase (HN) protein and exhibits a 50% enhancement in HN-dependent fusion over wild-type (wt) F protein. Here, we...

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Detalhes bibliográficos
Main Authors: Li, Jianrong, Melanson, Vanessa R., Mirza, Anne M., Iorio, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538552/
https://ncbi.nlm.nih.gov/pubmed/15613345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1180-1190.2005
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