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Phenelzine Protects Brain Mitochondrial Function In Vitro and In Vivo following Traumatic Brain Injury by Scavenging the Reactive Carbonyls 4-Hydroxynonenal and Acrolein Leading to Cortical Histological Neuroprotection

Lipid peroxidation (LP) is a key contributor to the pathophysiology of traumatic brain injury (TBI). Traditional antioxidant therapies are intended to scavenge the free radicals responsible for either initiation or propagation of LP. A more recently explored approach involves scavenging the terminal...

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Detalhes bibliográficos
Publicado no:J Neurotrauma
Main Authors: Cebak, John E., Singh, Indrapal N., Hill, Rachel L., Wang, Juan A., Hall, Edward D.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385448/
https://ncbi.nlm.nih.gov/pubmed/27750484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2016.4624
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