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Continuous Infusion of Phenelzine, Cyclosporine A, or Their Combination: Evaluation of Mitochondrial Bioenergetics, Oxidative Damage, and Cytoskeletal Degradation following Severe Controlled Cortical Impact Traumatic Brain Injury in Rats

To date, all monotherapy clinical traumatic brain injury (TBI) trials have failed, and there are currently no Food and Drug Administration (FDA)–approved pharmacotherapies for the acute treatment of severe TBI. Due to the complex secondary injury cascade following injury, there is a need to develop...

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Detalhes bibliográficos
Publicado no:J Neurotrauma
Main Authors: Kulbe, Jacqueline R., Singh, Indrapal N., Wang, Juan A., Cebak, John E., Hall, Edward D.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962911/
https://ncbi.nlm.nih.gov/pubmed/29336204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2017.5353
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