Molecular Dynamics Simulation of the Influenza A(H3N2) Hemagglutinin Trimer Reveals the Structural Basis for Adaptive Evolution of the Recent Epidemic Clade 3C.2a

Influenza A(H3N2) has been a major cause of seasonal influenza in humans since 1968, and has evolved by antigenic drift under the constantly changing human herd immunity. Increasing evidence suggests that the antigenic change occasionally occurred concomitant with the alterations of the N-glycosylat...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Yokoyama, Masaru, Fujisaki, Seiichiro, Shirakura, Masayuki, Watanabe, Shinji, Odagiri, Takato, Ito, Kimito, Sato, Hironori
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385362/
https://ncbi.nlm.nih.gov/pubmed/28443077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00584
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