Molecular Dynamics Simulation of the Influenza A(H3N2) Hemagglutinin Trimer Reveals the Structural Basis for Adaptive Evolution of the Recent Epidemic Clade 3C.2a

Influenza A(H3N2) has been a major cause of seasonal influenza in humans since 1968, and has evolved by antigenic drift under the constantly changing human herd immunity. Increasing evidence suggests that the antigenic change occasionally occurred concomitant with the alterations of the N-glycosylat...

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Bibliographische Detailangaben
Veröffentlicht in:Front Microbiol
Hauptverfasser: Yokoyama, Masaru, Fujisaki, Seiichiro, Shirakura, Masayuki, Watanabe, Shinji, Odagiri, Takato, Ito, Kimito, Sato, Hironori
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385362/
https://ncbi.nlm.nih.gov/pubmed/28443077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00584
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