Characterization of a Large Cluster of Influenza A(H1N1)pdm09 Viruses Cross-Resistant to Oseltamivir and Peramivir during the 2013-2014 Influenza Season in Japan

Between September 2013 and July 2014, 2,482 influenza 2009 pandemic A(H1N1) [A(H1N1)pdm09] viruses were screened in Japan for the H275Y substitution in their neuraminidase (NA) protein, which confers cross-resistance to oseltamivir and peramivir. We found that a large cluster of the H275Y mutant vir...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Takashita, Emi, Kiso, Maki, Fujisaki, Seiichiro, Yokoyama, Masaru, Nakamura, Kazuya, Shirakura, Masayuki, Sato, Hironori, Odagiri, Takato, Kawaoka, Yoshihiro, Tashiro, Masato
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394804/
https://ncbi.nlm.nih.gov/pubmed/25691635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04836-14
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