In Vitro and In Vivo Mutational Analysis of the 3′-Terminal Regions of Hepatitis E Virus Genomes and Replicons

Hepatitis E virus (HEV) replication is not well understood, mainly because the virus does not infect cultured cells efficiently. However, Huh-7 cells transfected with full-length genomes produce open reading frame 2 protein, indicative of genome replication (6). To investigate the role of 3′-termina...

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Detalhes bibliográficos
Main Authors: Graff, Judith, Nguyen, Hanh, Kasorndorkbua, Chaiyan, Halbur, Patrick G., St. Claire, Marisa, Purcell, Robert H., Emerson, Suzanne U.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538530/
https://ncbi.nlm.nih.gov/pubmed/15613330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1017-1026.2005
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