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Mutations within Potential Glycosylation Sites in the Capsid Protein of Hepatitis E Virus Prevent the Formation of Infectious Virus Particles

Hepatitis E virus is a nonenveloped RNA virus. However, the single capsid protein resembles a typical glycoprotein in that it contains a signal sequence and potential glycosylation sites that are utilized when recombinant capsid protein is overexpressed in cell culture. In order to determine whether...

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Detalhes bibliográficos
Main Authors: Graff, Judith, Zhou, Yi-Hua, Torian, Udana, Nguyen, Hanh, St. Claire, Marisa, Yu, Claro, Purcell, Robert H., Emerson, Suzanne U.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224450/
https://ncbi.nlm.nih.gov/pubmed/18032496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01219-07
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