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Directed Evolution of Retrovirus Envelope Protein Cytoplasmic Tails Guided by Functional Incorporation into Lentivirus Particles

In contrast to most gammaretrovirus envelope proteins (Env), the Gibbon ape leukemia virus (GaLV) Env protein does not mediate the infectivity of human immunodeficiency virus type 1 (HIV-1) particles. We made use of this observation to set up a directed evolution system by creating a library of GaLV...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Merten, Christoph A., Stitz, Jörn, Braun, Gundula, Poeschla, Eric M., Cichutek, Klaus, Buchholz, Christian J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2005
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538528/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15613311/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.2.834-840.2005
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