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Diverse arrestin-recruiting and endocytic profiles of tricyclic antipsychotics acting as direct α(2A) adrenergic receptor ligands

The therapeutic mechanism of action underlying many psychopharmacological agents remains poorly understood, due largely to the extreme molecular promiscuity exhibited by these agents with respect to potential central nervous system targets. Agents of the tricyclic chemical class, including both anti...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Cottingham, Christopher, Che, Pulin, Zhang, Wei, Wang, Hongxia, Wang, Raymond X, Percival, Stefanie, Birky, Tana, Zhou, Lufang, Jiao, Kai, Wang, Qin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385157/
https://ncbi.nlm.nih.gov/pubmed/27956055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.12.004
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