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Diverse arrestin-recruiting and endocytic profiles of tricyclic antipsychotics acting as direct α(2A) adrenergic receptor ligands

The therapeutic mechanism of action underlying many psychopharmacological agents remains poorly understood, due largely to the extreme molecular promiscuity exhibited by these agents with respect to potential central nervous system targets. Agents of the tricyclic chemical class, including both anti...

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Bibliografiske detaljer
Udgivet i:Neuropharmacology
Main Authors: Cottingham, Christopher, Che, Pulin, Zhang, Wei, Wang, Hongxia, Wang, Raymond X, Percival, Stefanie, Birky, Tana, Zhou, Lufang, Jiao, Kai, Wang, Qin
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385157/
https://ncbi.nlm.nih.gov/pubmed/27956055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.12.004
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