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The β(2)-adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis
βarrestins mediate the desensitization of the β(2)-adrenergic receptor (β(2)AR) and many other G protein-coupled receptors (GPCRs). Additionally, βarrestins initiate the endocytosis of these receptors via clathrin coated-pits and interact directly with clathrin. Consequently, it has been proposed th...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The National Academy of Sciences
1999
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC22359/ https://ncbi.nlm.nih.gov/pubmed/10097102 |
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