The β(2)-adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis

βarrestins mediate the desensitization of the β(2)-adrenergic receptor (β(2)AR) and many other G protein-coupled receptors (GPCRs). Additionally, βarrestins initiate the endocytosis of these receptors via clathrin coated-pits and interact directly with clathrin. Consequently, it has been proposed th...

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Autors principals: Laporte, Stéphane A., Oakley, Robert H., Zhang, Jie, Holt, Jason A., Ferguson, Stephen S. G., Caron, Marc G., Barak, Larry S.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC22359/
https://ncbi.nlm.nih.gov/pubmed/10097102
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