Visual arrestin interaction with clathrin adaptor AP-2 regulates photoreceptor survival in the vertebrate retina

Arrestins bind ligand-activated, phosphorylated G protein-coupled receptors (GPCRs) and terminate the activation of G proteins. Additionally, nonvisual arrestin/GPCR complex can initiate G protein-independent intracellular signals through their ability to act as scaffolds that bring other signaling...

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Dettagli Bibliografici
Autori principali: Moaven, Hormoz, Koike, Yukihiro, Jao, Christine C., Gurevich, Vsevolod V., Langen, Ralf, Chen, Jeannie
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677467/
https://ncbi.nlm.nih.gov/pubmed/23690606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301126110
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