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Cryo-EM structure of a separase-securin complex at near-atomic resolution
Separase is a caspase-family protease that initiates chromatid segregation by cleaving the kleisin subunits (Scc1 and Rec8) of cohesin, and regulates centrosome duplication and mitotic spindle function through cleavage of kendrin and Slk19. To understand the mechanisms of separase regulation by secu...
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| 出版年: | Nat Struct Mol Biol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5385133/ https://ncbi.nlm.nih.gov/pubmed/28263324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3386 |
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