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Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles

Although electron cryo-microscopy (cryo-EM) single-particle analysis has become an important tool for structural biology of large and flexible macro-molecular assemblies, the technique has not yet reached its full potential. Besides fundamental limits imposed by radiation damage, poor detectors and...

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Bibliographic Details
Main Authors: Bai, Xiao-chen, Fernandez, Israel S, McMullan, Greg, Scheres, Sjors HW
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576727/
https://ncbi.nlm.nih.gov/pubmed/23427024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00461
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