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Cryo-EM structure of a separase-securin complex at near-atomic resolution
Separase is a caspase-family protease that initiates chromatid segregation by cleaving the kleisin subunits (Scc1 and Rec8) of cohesin, and regulates centrosome duplication and mitotic spindle function through cleavage of kendrin and Slk19. To understand the mechanisms of separase regulation by secu...
Tallennettuna:
| Julkaisussa: | Nat Struct Mol Biol |
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| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5385133/ https://ncbi.nlm.nih.gov/pubmed/28263324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3386 |
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